BIOMECHANICS, BIOENGINEERING AND MATHEMATICAL BIOLOGY Seminar

PROGRAM

Plan rada Seminara iz Biomehanike, bioinžinjeringa i matematičke biologije za NOVEMBAR 2021.

Ponedeljak, 15.11.2021. u 16:00, Live stream
Nenad Filipovic, Faculty of Engineering University of Kragujevac, Kragujevac, Serbia; BioIRC Bioengineering Research and Development center, Kragujevac, Serbia
SILICOFCM PLATFORM, IN SILICO CLINICAL TRIALS FOR CARDIOVASCULAR DISEASE
In silico clinical trials are the future of medicine and virtual testing and simulation are the future of medical engineering. Usage of computational platform will provide lower costs and less required time for developing new models of medical devices and drugs.
SILICOFCM is a multi-modular, innovative in silico clinical trials solution for the design and functional optimization of whole heart performance and monitoring effectiveness of pharmacological treatment, with the aim to reduce animal studies and human clinical trials. The SILICOFCM platform is based on the integrated multidisciplinary and multiscale methods for analysis of patient-specific data and development of patient-specific models for monitoring and assessment of patient condition through the course of disease.
The platform combines data from multiple data sets collected at multiple scales with sophisticated and continuously developing computational models, therefore, following the information flow across all length scales from a gene mutation to organ dysfunction.
The workflows of multiple modules implemented in the SILICOFCM computational cloud platform are devoted to the optimization of whole heart performance and monitoring of effectiveness of pharmacological treatment. This approach will open a new avenue for accelerating new drug development or for testing drugs used in clinical practice.